Selective inhibition of anaerobic ubiquinone biosynthesis in Pseudomonas aeruginosa
Julie Michaud, Yvan Caspar, Olivier Lerouxel, Tuan Anh Dinh, Philippe Simon, Murielle Lombard, Ludovic Pélosi
This study identifies pABA as an inhibitor of anaerobic ubiquinone biosynthesis in Pseudomonas aeruginosa, targeting its unique O2-independent pathway to disrupt anaerobic metabolism.
bioRxiv · Sep 24, 2026 · PreprintMicrobiology