Ludovic Pélosi

This study identifies UbiB as an ATP-dependent decarboxylase in bacterial ubiquinone biosynthesis, showing it can replace the UbiX/UbiD system in Escherichia coli.

This study identifies pABA as an inhibitor of anaerobic ubiquinone biosynthesis in Pseudomonas aeruginosa, targeting its unique O2-independent pathway to disrupt anaerobic metabolism.

This study maps the distribution of isoprenoid quinones in Bacteria using genomic data and phylogenetic analysis, revealing new insights into their evolutionary history and metabolic adaptations.

The paper identifies a novel ancestral high redox potential quinone, methyl-plastoquinone, and shows its evolutionary origin predates the Great Oxygenation Event.

This study identifies COQ4 as catalyzing the oxidative decarboxylation of the C1 carbon in CoQ biosynthesis in eukaryotic cells.