An LSEC-focused computational drug repurposing platform for liver fibrosis: Identification of vorinostat and other LSEC-protective candidates
Rui Zuo, Mi Wang, Y Q Wang, Jenny Z. Hu, Alexandra K. Moura, Dan Wang, Pin-Lan Li, Mingfu Wu, Tahir Hussain, Wei Gao, Xiang Li, Yang Zhang
This paper develops a computational platform to repurpose drugs for liver fibrosis by focusing on LSECs, identifying vorinostat and other candidates that protect LSECs.
bioRxiv · May 27, 2026 · PreprintPharmacology & Toxicology