Circuit-selective cognitive vulnerability to environmental stress: multi-domain assessment of space radiation in both sexes reveals countermeasure trade-offs
Sheridan A O'Connor, Pragatee Narain, Amishi Mahajan, Grace L. Bancroft, Harley A. Haas, Elise Wallen-Friedman, Shubha Vasisht, Hajime Takano, Frederico C. Kiffer, Amelia J. Eisch, Sanghee Yun
This study assesses how space radiation affects cognitive circuits in male and female mice, revealing sex-specific vulnerabilities and trade-offs in neuroprotective interventions.
bioRxiv · Mar 30, 2026 · PreprintAnimal Behavior & Cognition