Rpl12 paralog dependent TOR-signaling controls the expression of ribosome preservation factor Stm1
Sourav Sharma, Pratyush Kumar Datta, Suresh Singh Yadav, Imran Pancha, Rohini Ravindran Nair
This study shows that Rpl12 paralogs regulate TOR signaling and ribosome stability, with RPL12b loss reducing Stm1 levels and extending chronological lifespan in yeast.
bioRxiv · Mar 26, 2026 · PreprintCell Biology