Obesity promotes urinary tract infection by disrupting urothelial immune defenses
Laura Schwartz, Kristin Salamon, Aaron A. Simoni, Israel Cotzomi-Ortega, Yuriko I. Sánchez-Zamora, Sarah C. Linn, Preeti John, Juan de Dios Ruiz‐Rosado, Ashley R. Jackson, Xin Wang, John David Spencer
This study shows obesity increases UTI risk by altering bladder immune defenses through focal adhesion kinase activation in mice and human cells.
iScience · Oct 25, 2025Peer-reviewedCell Biology