Accelerating antibiotic discovery from Earth's isolated habitats through protein language models and microfluidics
Zixin Kang, Haohong Zhang, Qize Zhou, Jiayi Liu, Kouyi Zhou, Peng Chen, Bifeng Liu, Kang Ning
The paper develops MicroSPEAR, a framework combining a protein language model and microfluidics to discover and validate antimicrobial peptides from isolated habitats.
bioRxiv · Nov 13, 2025 · PreprintBioinformatics