R. A. Murphy

Antimicrobial peptide glatiramer acetate targets Pseudomonas aeruginosa lipopolysaccharides to breach membranes without altering lipopolysaccharide modification

This study shows glatiramer acetate binds and neutralizes Pseudomonas aeruginosa lipopolysaccharides and extracellular DNA, enhancing antibiotic efficacy without inducing resistance mechanisms.

Synergistic Activity of Repurposed Peptide Drug Glatiramer Acetate with Tobramycin Against Cystic Fibrosis Pseudomonas aeruginosa

This study shows that glatiramer acetate enhances tobramycin's effectiveness against Pseudomonas aeruginosa in cystic fibrosis patients by reducing MICs and disrupting bacterial membranes.

Uncertainty avoidance versus conditioned reinforcement: exploring paradoxical choice in rats

This study investigates why rats prefer information-giving options despite no functional benefit, finding that both uncertainty reduction and conditioned reinforcement influence their choices.

statSuma: automated selection and performance of statistical comparisons for microbiome studies

statSuma automates statistical test selection for microbiome studies by analyzing data structures and recommending appropriate tests for pairwise and multicategorical comparisons.

uniForest: an unsupervised machine learning technique to detect outliers and restrict variance in microbiome studies

uniForest applies Isolation Forests to microbiome data to detect outliers and reduce variance, achieving significant variance reduction in community structure and alpha diversity.