Pneumococcal Extracellular Vesicles Mediate Horizontal Gene Transfer via the Transformation Machinery
S. Werner Lass, S. Camphire, B. E. Smith, R. A. Smith, J. A. Prentice, S. S. Yerneni, A. Arun, A. A. Bridges, J. W. Rosch, J. F. Conway, P. Campbell, N. L. Hiller
This paper shows pneumococcal extracellular vesicles carry DNA that can be transferred to competent cells via the transformation machinery, promoting horizontal gene transfer and potential antibiotic resistance spread.
bioRxiv · Dec 15, 2023 · PreprintMicrobiology