P. Campbell

Pneumococcal Extracellular Vesicles Mediate Horizontal Gene Transfer via the Transformation Machinery

This paper shows pneumococcal extracellular vesicles carry DNA that can be transferred to competent cells via the transformation machinery, promoting horizontal gene transfer and potential antibiotic resistance spread.

Geographic variation in the songs of two closely related song-learning species, Anna's and Costa's hummingbird (Calypte anna, C. costae)

This study examines geographic variation in songs of two hummingbird species, finding that Anna's hummingbirds show population-level song variation while Costa's hummingbirds show minor frequency differences.

Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease

The paper identifies adaptive pathways in metabolic liver disease by selecting somatically mutated clones in mice and humans, finding mutations that ameliorate lipotoxicity and promote clonal expansion.

Fanconi Anemia Pathway Deficiency Drives Copy Number Variation in Squamous Cell Carcinomas

This paper shows that FA pathway deficiency in squamous cell carcinomas leads to high structural variant rates and copy number alterations, linking genomic instability to tumor progression.

The longitudinal dynamics and natural history of clonal haematopoiesis

This study tracks clonal haematopoiesis clones over time, finding that mutation type influences growth rates and malignant risk.

Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

This study shows that acetyl-CoA metabolism in fatty liver disease leads to histone hyperacetylation, DNA damage, and increased mutation risk, contributing to hepatocellular carcinoma.

High-speed widefield handheld swept-source OCT angiography with a VCSEL light source

This paper presents a high-speed handheld OCT/OCTA system for retinal imaging in clinical settings, demonstrating its use in neonatal and surgical patients.

Haldane's rule in the placenta: sex-biased misregulation of the Kcnq1 imprinting cluster in hybrid mice

This study investigates sex-biased misregulation of the Kcnq1 imprinting cluster in hybrid mice placenta, linking it to Haldane's rule and hybrid inviability.

The PINK1 - Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells

The study shows that the PINK1-Parkin mitophagy pathway is not functional in peripheral blood mononuclear cells, making them unsuitable for mitophagy analysis in Parkinson's disease.

Distinct evolutionary trajectories of V1R clades across mouse species

The paper analyzes V1R receptor evolution across five Mus species, identifying distinct clade-specific evolutionary patterns and candidate receptors for social and predator signal detection.

Placental effects on maternal brain revealed by disrupted placental gene expression in mouse hybrids

The paper shows that altered placental gene expression in mouse hybrids affects maternal brain gene expression, suggesting paternal influence on maternal behavior through placental signaling.

Patterns of urine scent mark pheromone evolution in house mice and relatives (Muridae: Mus)

This study examines the evolution of urinary pheromone proteins (MUPs) in house mice and relatives, revealing how amino acid variants and gene expression patterns contribute to pheromone diversity and sexual selection.