Global Pannexin 1-deletion increases tumor-infiltrating lymphocytes in the BRAF/Pten mouse melanoma model.
R. E. Sanchez-Pupo, G. Finch, D. E. Johnston, H. Craig, R. Abdo, K. J. Barr, S. M. Kerfoot, L. Dagnino, S. Penuela
This study shows that deleting Pannexin 1 in a melanoma mouse model increases CD8+ T cell infiltration without affecting tumor growth or survival.
bioRxiv · Jul 28, 2023Cancer Biology