Increased HIF-2α Activity in the Nucleus Pulposus Causes Intervertebral Disc Degeneration in the Aging Mouse Spine
S. Johnston, M. Tsingas, R. Ain, R. Barve, M. V. Risbud
This study shows that increased HIF-2α activity in nucleus pulposus cells accelerates intervertebral disc degeneration in aging mice.
bioRxiv · Dec 22, 2023 · PreprintCell Biology