Engineered Active Zymogen of Microbial Transglutaminase
R. Ariyoshi, T. Matsuzaki, R. Sato, K. Minamihata, K. Hayashi, R. Wakabayashi, M. Goto, N. Kamiya
This paper designs an engineered active zymogen of microbial transglutaminase (EzMTG) that exhibits cross-linking activity without requiring proteolysis, and identifies mutations that balance binding affinity and catalytic activity.
bioRxiv · Oct 9, 2023 · PreprintBiochemistry