MicrobiologybioRxiv
The monothiol glutaredoxin Grx4 interacts with the Cryptococcus iron regulator Cir1 and regulates iron homeostasis and virulence in the Cryptococcus neoformans
R. Attarian, G. Hu, M. Caza…·J. W. Kronstad
This study identifies Grx4 as a binding partner of Cir1 in Cryptococcus neoformans, showing that Grx4 regulates iron homeostasis and virulence through its interaction with Cir1.
DOI 10.1128/mbio.02377-18