Author

E. Sanchez-Leon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:fungi (other)· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. W. Kronstad· 3 shared G. Hu· 2 shared W. H. Jung· 2 shared A. Brisland· 1 shared A. S. Ibrahim· 1 shared B. Black· 1 shared C. Boone· 1 shared C. Diehl· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

J. W. Kronstad

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3 papers

Recent·Most cited

Brilacidin, a novel antifungal agent against Cryptococcus neoformans

C. Diehl, C. F. Pinzan, P. A. de Castro, E. Delbaje, L. G. Carnero, E. Sanchez-Leon, K. Bhalla, J. W. Kronstad, D.-g. Kim, T. L. Doering, S. Alkhazraji, N. N. Mishra, A. S. Ibrahim, M. Yoshimura, L. A. V. Isuhuayla, , G. H. Goldman

This paper identifies brilacidin as a novel antifungal agent effective against Cryptococcus neoformans, showing it reduces fungal survival in macrophages and potentiates existing antifungals.

bioRxiv · Apr 10, 2024 · PreprintMicrobiology

The interplay between electron transport chain function and iron regulatory factors influences melanin formation in Cryptococcus neoformans

P. Xue, E. Sanchez-Leon, G. Hu, C. Lee, B. Black, A. Brisland, H. Li, W. H. Jung, J. W. Kronstad

This paper investigates how mitochondrial electron transport chain function and iron regulatory factors influence melanin formation in Cryptococcus neoformans, revealing a link between mitochondrial dysfunction, redox homeostasis, and virulence.

bioRxiv · Feb 15, 2024 · PreprintMicrobiology

The monothiol glutaredoxin Grx4 interacts with the Cryptococcus iron regulator Cir1 and regulates iron homeostasis and virulence in the Cryptococcus neoformans

R. Attarian, G. Hu, M. Caza, E. Sanchez-Leon, D. Croll, E. Do, H. Bach, T. Missall, J. Lodge, W. H. Jung, J. W. Kronstad

This study identifies Grx4 as a binding partner of Cir1 in Cryptococcus neoformans, showing that Grx4 regulates iron homeostasis and virulence through its interaction with Cir1.

bioRxiv · Jun 28, 2018Microbiology