Effects of altering histone post-translational modifications on mitotic chromosome structure and mechanics
R. Biggs, A. D. Stephens, P. Liu, J. F. Marko
This study investigates how histone post-translational modifications affect mitotic chromosome stiffness using force measurements and epigenetic drugs, finding that methylation, not acetylation, contributes to mitotic structure.
bioRxiv · Jan 4, 2019Cell Biology