R. Brewster

Integrative Single-Cell RNA and ATAC Sequencing Reveals the Impact of Chronic Cigarette Smoking on Lung Epithelial Responses to Influenza and Hyperoxia

This study uses scRNA-seq and scATAC-seq to show chronic cigarette smoke exposure enhances inflammatory and survival pathways in lung epithelial responses to influenza and hyperoxia.

Gut Microbiome Profiling of a Rural and Urban South African Cohort Reveals Biomarkers of a Population in Lifestyle Transition

This study compares gut microbiomes of rural and urban South African women to identify microbial biomarkers linked to lifestyle and obesity.

Probing mechanisms of transcription elongation through cell-to-cell variability of RNA polymerase

The paper uses stochastic simulations to analyze cell-to-cell variability in RNA polymerase numbers and distances to infer transcriptional regulation mechanisms in yeast ribosomal genes.