Unveiling the role of osteosarcoma-derived secretome in premetastatic lung remodeling
S. Almeida, L. Santos, G. Ribeiro, H. Ferreira, N. Lima, R. Caetano, M. Abreu, M. Zuzarte, A. S. Ribeiro, A. Paiva, T. Martins-Marques, P. Teixeira, R. Almeida, J. Casanova, H. Girao, , C. Gomes
The paper investigates how osteosarcoma secretome remodels the lung microenvironment to promote metastasis using mouse models and multi-omics analysis.
bioRxiv · May 6, 2023Cancer Biology