Treatment-shortening effect of a novel regimen combining high-dose rifapentine and clofazimine in pathologically distinct mouse models of tuberculosis
V. Saini, N. C. Ammerman, Y. S. Chang, R. Tasneen, R. Chaisson, S. K. Jain, E. Nuermburger, J. H. Grosset
This study tests a new TB treatment regimen combining high-dose rifapentine and clofazimine in mouse models, finding it more effective than either drug alone in shortening treatment duration.
bioRxiv · Feb 21, 2019Microbiology