Isolating Small Extracellular Vesicles from Small Volumes of Blood Plasma using size exclusion chromatography and density gradient ultracentrifugation: A Comparative Study
F. Kong, M. Upadya, A. S. Wong, R. Dalan, M. Dao
This study compares SEC-DGUC and DGUC-SEC protocols for isolating high-purity sEVs from small plasma volumes, finding SEC-DGUC yields higher protein and RNA content.
bioRxiv · Oct 30, 2023 · PreprintBioengineering