Molecular and functional diversity of distinct subpopulations of extracellular vesicles from stressed pancreatic beta cells: implications for autoimmunity
K. R. Giri, L. De Beaurepaire, D. Jegou, M. Lavy, M. Mosser, A. Dupont, R. Fleurisson, L. Dubreil, M. Collot, P. Van Endert, J.-M. Bach, G. Mignot, S. Bosch
This study compares extracellular vesicles from stressed pancreatic beta cells and finds that inflammation increases vesiculome volume and immune-stimulatory material release, with differential sorting of cytokines and microRNAs into subpopulations.
bioRxiv · Mar 26, 2020 · PreprintImmunology