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R. J. Gupta

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Evolutionary Biology· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

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A. S. Petrov· 1 shared C. Alvarez-Carreno· 1 shared L. D. Williams· 1 shared

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1 shared paperEvolutionary Biology

A. S. Petrov

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Evolutionary BiologybioRxivPreprintMar 30, 2022

The Evolution of Protein Folds by Creative Destruction

C. Alvarez-Carreno, R. J. Gupta, A. S. Petrov, L. D. Williams

The paper identifies a mechanism called creative destruction that explains how new protein folds evolve from existing ones through gene duplication, merging, and adaptation.

DOI 10.1101/2022.03.30.486258

protein structureprotein sequence