Author

R. L. Dannenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:DNA methylation· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

K. G. Pytko· 3 shared M. Hedglin· 3 shared E. Antony· 1 shared J. A. Cardina· 1 shared J. L. Norris· 1 shared K. A. Eckert· 1 shared L. O. Rogers· 1 shared S. Kuppa· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBiochemistry

K. G. Pytko

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Author profile →

3 papers

Recent·Most cited

Replication of 25 microsatellite sequences by human DNA polymerase delta holoenzymes is dependent on dNTP and RPA levels

K. G. Pytko, R. L. Dannenberg, K. A. Eckert, M. Hedglin

This study investigates how human DNA polymerase delta holoenzymes replicate [AT/TA]25 microsatellite sequences and finds that replication efficiency depends on dNTP and RPA levels.

bioRxiv · Nov 7, 2023Biochemistry

Interplay of macromolecular interactions during assembly of human DNA polymerase δ holoenzymes and initiation of DNA synthesis

J. L. Norris, L. O. Rogers, K. G. Pytko, R. L. Dannenberg, S. Perreault, V. Kaushik, S. Kuppa, E. Antony, M. Hedglin

This study uses FRET assays to show how RPA interactions at P/T junctions facilitate Pol δ holoenzyme assembly and DNA synthesis efficiency.

bioRxiv · May 9, 2023 · PreprintBiochemistry

High resolution studies of DNA lesion bypass by human DNA polymerase δ holoenzymes

R. L. Dannenberg, J. A. Cardina, K. G. Pytko, M. Hedglin

This study quantitatively examines how human DNA polymerase δ holoenzymes handle DNA lesions during replication, showing they can replicate lesions and their effects depend on lesion type and proofreading.

bioRxiv · Jun 30, 2022Biochemistry