CDK-4 regulates nucleolar size and metabolism at the cost of late life fitness in C. elegans
R. L. Webster, M. Quintana, R. Kafri, B. Derry
This study shows that CDK-4 in C. elegans regulates nucleolar size and metabolism, leading to improved early life thermotolerance but reduced longevity.
bioRxiv · Jan 25, 2024Cell Biology