Replacing reprogramming factors with antibodies selected from autocrine antibody libraries
J. W. Blanchard, J. Xie, N. El-Mecharrafie, S. Gross, S. Lee, R. Lerner, K. K. Baldwin
This study identifies antibodies from autocrine libraries that can replace reprogramming factors like Sox2 and Oct4, enabling iPSC generation through membrane-initiated signaling pathways.
bioRxiv · Jun 27, 2017Cell Biology