Engineering selectivity of Cutibacterium acnes phages by epigenetic imprinting
N. Knoedlseder, G. Nevot, M. Fabrega, J. Mir-Pedrol, M. Sanvicente, N. Campana-Sanz, R. Lood, M. Güell
The paper demonstrates that phages can be engineered to selectively kill specific C. acnes strains by acquiring methylation patterns from infected strains.
bioRxiv · Dec 19, 2021Microbiology