Mycobacterial resistance to zinc poisoning requires assembly of P-ATPase-containing membrane metal efflux platforms
Y.-M. Boudehen, M. Faucher, X. Marechal, R. Miras, J. Rech, O. Seneque, M. Wallat, P. Demange, J.-Y. Bouet, O. Saurel, P. Catty, C. Gutierrez, O. Neyrolles
The paper identifies PacL1 as a scaffold that assembles P-ATPase-containing metal efflux platforms in Mycobacterium tuberculosis, contributing to zinc resistance.
bioRxiv · Oct 1, 2021Microbiology