C. Gutierrez

Nucleotidyltransferase toxin MenT targets and extends the aminoacyl acceptor ends of serine tRNAs in vivo to control Mycobacterium tuberculosis growth

This study identifies MenT3 as a tRNA nucleotidyltransferase that modifies serine tRNAs in Mycobacterium tuberculosis, affecting bacterial growth and revealing its role in infection.

Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in Black American and White American patients with TNBC

This study uses spatial omics to identify distinct tumor microenvironment profiles in Black and White American TNBC patients, linking them to different immunosuppressive mechanisms and clinical outcomes.

Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration

This study shows that glutathione accelerates cell cycle progression and reprogramming in plant regeneration by promoting rapid division and nuclear changes near injury sites.

Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

This study investigates the role of VirR in Mycobacterium tuberculosis vesicle production and links it to cell wall remodeling, suggesting potential therapeutic targets.

The Arabidopsis SHORTROOT network coordinates shoot apical meristem development with auxin dependent lateral organ initiation

This paper identifies SHR and its associated transcription factors as regulators of shoot apical meristem development and lateral organ initiation in Arabidopsis, showing their role in cell division and auxin-dependent processes.

Cell-cycle status of male and female gametes during Arabidopsis reproduction

The paper investigates the cell-cycle status of male and female gametes in Arabidopsis during fertilization, finding both are arrested before DNA replication and initiate replication only during fertilization.

Stem cell regulators control a G1 duration gradient in the plant root meristem

The paper shows that stem cell regulators create a G1 duration gradient in the plant root meristem, with mutants disrupting this gradient.

Mycobacterial resistance to zinc poisoning requires assembly of P-ATPase-containing membrane metal efflux platforms

The paper identifies PacL1 as a scaffold that assembles P-ATPase-containing metal efflux platforms in Mycobacterium tuberculosis, contributing to zinc resistance.

FBL17 targets CDT1a for degradation in early S-phase to prevent Arabidopsis genome instability

The paper identifies FBL17 as the E3 ligase responsible for CDT1a degradation in early S-phase of Arabidopsis, preventing genome instability.

An improved Xer-cise technology for the generation of multiple unmarked mutants in Mycobacteria

The paper improves the Xer-cise technique to generate multiple unmarked mutants in Mycobacteria by using dif site variants that prevent recombination between cassettes, enhancing genetic stability.

Expressed barcodes enable clonal characterization of chemotherapeutic responses in chronic lymphocytic leukemia

This paper develops a method to study clonal responses to chemotherapy in CLL by combining barcoding with single-cell RNA sequencing, revealing that rare drug-tolerant clones dominate post-treatment populations.

BioModelos: a collaborative online system to map species distributions

BioModelos is a collaborative system that develops species distribution models using expert input, making validated models publicly available for conservation applications.

Differences in firing efficiency, chromatin and transcription underlie the developmental plasticity of Arabidopsis originome

The paper examines the originome and chromatin landscape of Arabidopsis thaliana at two developmental stages, revealing how ORI firing efficiency and chromatin features change with development.