Long-term exposure to polyamines leads to bacteriophage resistance in Pseudomonas aeruginosa
Raymond Finnerty, Christina Lim, Patrick R. Secor, C. W. Marshall
This study shows that long-term exposure to putrescine drives phage resistance in Pseudomonas aeruginosa through mutations in type IV pili genes, even without prior phage exposure.
bioRxiv · Jul 16, 2026 · PreprintMicrobiology