Patrick R. Secor

This study shows that long-term exposure to putrescine drives phage resistance in Pseudomonas aeruginosa through mutations in type IV pili genes, even without prior phage exposure.

The paper identifies a prophage-encoded sRNA, svsR, that reduces lytic phage infection in AIEC by repressing maltodextrin transport genes, thereby limiting phage receptor expression.

The paper investigates Pf phage transmission in Pseudomonas aeruginosa airway infections in cystic fibrosis patients, finding vertical transmission within lineages and new superinfections by Pf+ strains.

This study shows Pf phages and sputum polymers reduce antibiotic diffusion through electrostatic binding and liquid crystal formation in chronic Pseudomonas aeruginosa infections.

This study deletes Pf prophages from P. aeruginosa isolates and examines their impact on quorum sensing, biofilm formation, and virulence traits.

This study characterizes the bacteriophage phiBB-1 using proteomics and long-read sequencing, revealing its packaging mechanisms and role in gene transfer in Borrelia burgdorferi.

VIBES automates prophage annotation in bacterial genomes and provides visualization tools, demonstrating its utility across 1,072 Pseudomonas genomes.

The paper identifies PfsE as a Pf phage protein that inhibits PQS quorum sensing and type IV pili extension, enhancing viral replication and protecting the host from competing phages.