A non-canonical lysosome biogenesis pathway generates Golgi-associated lysosomes during epidermal differentiation
Sarmistha Mahanty, Shruthi Shirur Dakappa, Rezwan Shariff, Saloni Patel, Mruthyunjaya Mathapathi Swamy, Amitabha Majumdar, Subba Rao Gangi Setty
This study identifies a non-canonical lysosome biogenesis pathway during epidermal differentiation that generates Golgi-associated lysosomes (GALs) through ER stress and ATF6 signaling.
bioRxiv · May 1, 2018 · PreprintCell Biology