Author

Richard Moore

BC Cancer AgencyPrimary ORCID profile (0009-0003-8804-9211 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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RICHARD MOOREiD3 papers

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Daniel LaiiD· 2 shared Adrian N. C. Wan· 1 shared Alex MirandaiD· 1 shared Alexander Adrian-Hamazaki· 1 shared Alexandre Bouchard-Côté· 1 shared Ali BashashatiiD· 1 shared Allen W. ZhangiD· 1 shared Amelia RichteriD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Daniel LaiORCID

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3 papers

Recent·Most cited

Chromosomal mutational signatures of DNA damaging agents at single cell resolution

Mirela Andronescu, Alexander Adrian-Hamazaki, Damian Yap, William Daniels, Armaghan Sarvar, Elena Zaikova, Benjamin Furman, Vinci Au, Amelia Richter, Michael Van Vliet, Caroline Baril, Beixi Wang, Sean Beatty, Farhia Kabeer, Ciara H. O’Flanagan, , Samuel A. J. R. Aparicio

This paper develops a framework to analyze chromosomal mutational patterns at single-cell resolution, revealing drug-induced mutational signatures in human tissues.

bioRxiv · Sep 7, 2026 · PreprintCancer Biology

Loss of TRIM21 drives UVB-induced systemic inflammation by regulating DNA-sensing pathways

Gantsetseg Tumurkhuu, Graziela Perri, Richard Moore, Lihong Huo, Arati Naveen Kumar, Richard I. Ainsworth, TRINITEE R. OLIVER, Gabriela De Los Santos, David R. Gibb, Jessica Carrière, Jeong Min Yu, Rachel Abuav, Lindsy J. Forbess, Daniel J. Wallace, MARIKO L. ISHIMORI, , Caroline Anne Jefferies

This study shows that loss of TRIM21 increases UVB-induced systemic inflammation by enhancing IFN expression through impaired STING signaling in mice.

Arthritis & Rheumatology · Jun 17, 2025Peer-reviewedImmunology

The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancer

Allen W. Zhang, Andrew McPherson, Katy Milne, David R. Kroeger, Phineas T. Hamilton, Alex Miranda, Tyler Funnell, Sonya Laan, Dawn R. Cochrane, Jamie L.P. Lim, Winnie Yang, Andrew Roth, Maia A. Smith, Camila de Souza, Julie Ho, , Sohrab P. Shah

The paper analyzes the interaction between tumor and immune clones in ovarian cancer, finding that immune contexture patterns mirror malignant spread and that foldback inversions correlate with poor outcomes.

bioRxiv · Oct 4, 2017 · PreprintCancer Biology