The smoking cessation drug cytisine requires systemically circulating estrogen for sex-specific neuroprotection in female parkinsonian mice
Sara M. Zarate, Roger C. Garcia, Gauri Pandey, Rahul Srinivasan
This study shows that cytisine's neuroprotective effect in female Parkinsonian mice depends on systemic estrogen, with estrogen depletion reversing this protection.
bioRxiv · Mar 21, 2024 · PreprintNeuroscience