Author

Ruby Pitts

Vanderbilt University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:Ribo-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexis B. RobersoniD· 2 shared Bavavarshini Tamilselvam· 2 shared James MarksiD· 2 shared Sezen MeydaniD· 2 shared Brian C. GriebiD· 1 shared Nicholas R. GuydoshiD· 1 shared Pedro H Ayres-GalhardoiD· 1 shared William P. TanseyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Alexis B. RobersonORCID

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2 papers

Recent·Most cited

Quantitative profiling of basal and stress-induced ribosome collisions

James Marks, Pedro H Ayres-Galhardo, Bavavarshini Tamilselvam, Alexis B. Roberson, Ruby Pitts, Nicholas R. Guydosh, Sezen Meydan

The paper quantifies disome levels across the transcriptome in yeast and human cells under basal and stress conditions, showing stress-induced increases and context-dependent redistribution.

bioRxiv · Oct 6, 2026 · PreprintMolecular Biology

5-Azacytidine incorporation into mRNAs disrupts translation and induces ribosome collisions

Alexis B. Roberson, James Marks, Ruby Pitts, Bavavarshini Tamilselvam, Brian C. Grieb, William P. Tansey, Sezen Meydan

This study shows 5-AzaC incorporation into mRNAs disrupts translation, causes ribosome collisions, and activates stress responses, contributing to its cytotoxicity beyond DNA hypomethylation.

bioRxiv · Mar 31, 2026 · PreprintBiochemistry