Author

Ruohan Ren

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:transformer / foundation model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein design· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Anthony SantellaiD· 1 shared Dali WangiD· 1 shared Erin Haus· 1 shared Hongyu YuiD· 1 shared Jiahao TengiD· 1 shared Sihui Mao· 1 shared Stephen S.‐T. YauiD· 1 shared Yangtianze TaoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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10 top collaborators · 20 mutual co-author links

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1 shared paperDevelopmental Biology

Anthony SantellaORCID

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2 papers

Recent·Most cited

A Single-cell Spatiotemporal Manifold of Tissue Morphology and Dynamics

Erin Haus, Anthony Santella, Yichi Xu, Ruohan Ren, Dali Wang, Zhirong Bao

This paper introduces a learned single-cell spatiotemporal manifold to analyze tissue morphology and dynamics over time.

Cell Reports Methods · Sep 1, 2026Peer-reviewedDevelopmental Biology

Evolution is All You Need in Promoter Design and Optimization

Ruohan Ren, Hongyu Yu, Jiahao Teng, Sihui Mao, Zixuan Bian, Yangtianze Tao, Stephen S.‐T. Yau

This paper introduces CAPE, a model that improves promoter strength prediction by incorporating evolutionary information, achieving state-of-the-art results and enabling in silico directed evolution.

Briefings in Bioinformatics · Jul 25, 2024Peer-reviewedSynthetic Biology