Evolution is All You Need in Promoter Design and Optimization
Ruohan Ren, Hongyu Yu, Jiahao Teng, Sihui Mao, Zixuan Bian, Yangtianze Tao, Stephen S.‐T. Yau
This paper introduces CAPE, a model that improves promoter strength prediction by incorporating evolutionary information, achieving state-of-the-art results and enabling in silico directed evolution.
Briefings in Bioinformatics · Jul 25, 2024Peer-reviewedSynthetic Biology