Author

Ryan Dennis

Chapman University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

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Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Brandon Foley· 1 shared Gennady M. VerkhivkeriD· 1 shared Lucas Turano· 1 shared Will GatliniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Brandon Foley

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1 paper

Recent·Most cited

Frustration Quenching and Network Topology of the Energy Landscape as Primary Determinants of Protein-Ligand Binding Pose Prediction by Deep Learning Models

Lucas Turano, Brandon Foley, Ryan Dennis, Will Gatlin, Gennady M. Verkhivker

This paper shows that deep learning models' performance in predicting protein-ligand binding poses depends on the energy landscape's frustration quenching and network topology, not algorithmic flaws.

bioRxiv · Oct 9, 2026 · PreprintBiophysics