Osteocyte State Transitions Modulate Bone Remodeling During Early Skeletal Aging
Ryosuke Denda, Anhao Liu, Mikihito Hayashi, Cheng Wang, Haruhiko Akiyama, Hiroshi Takayanagi, Mitsuru Saito, Tomoki Nakashima
This study investigates how osteocyte state transitions affect bone remodeling during early skeletal aging, finding age-dependent changes in osteocyte subpopulations and their impact on bone mass.
bioRxiv · Aug 14, 2026 · PreprintMolecular Biology