IFNγ induces epithelial reprogramming driving CXCL11-mediated T cell migration
A. Cutilli, S. A. Jansen, F. Paolucci, M. Mokry, E. Mocholi, C. A. Lindemans, P. J. Coffer
This study shows IFNγ reprograms intestinal epithelial organoids to secrete CXCL11, which enhances T cell migration without affecting T cell activation.
bioRxiv · Feb 3, 2024Immunology