Targeting the mitochondrial RNA methyltransferase TRMT61B reveals new therapeutic opportunities in aneuploid cancer cells
A. Martin, B. Vilaplana-Marti, R. I. Macias, A. Martinez-Ramirez, A. Cerezo, P. Cabezas-Sainz, M. G. Asensio, C. Epifano, S. Amarilla, D. Gomez-Dominguez, I. Hernandez, E. Caleiras, J. Camps, R. Barderas, L. Sanchez, , I. Perez de Castro
This study identifies TRMT61B as a therapeutic target in aneuploid cancer cells by showing its role in mitochondrial function and tumor progression.
bioRxiv · Apr 25, 2021Cancer Biology