NGFR regulates germinal center B-cell activation and negative selection
A. Hernandez-Barranco, M. S. Mazariegos, V. Santos, E. Caleiras, L. Nogues, F. Mourcin, S. Leonard, C. Oblet, S. Genebrier, D. Rossille, A. Benguria, E. Vazquez, A. Dopazo, A. Efeyan, A. Ortega-Molina, , H. Peinado
This study shows that NGFR regulates germinal center B-cell activation and negative selection by maintaining GC structure and function, affecting antibody production and immune tolerance.
bioRxiv · Jul 14, 2023 · PreprintImmunology