Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures
A. Vanderheiden, P. Ralfs, T. Chirkova, A. A. Upadhyay, M. G. Zimmerman, S. Bedoya, H. Aoued, G. K. Tharp, K. Pellegrini, A. C. Lowen, V. D. Menachery, L. J. Anderson, A. Grakoui, S. E. Bosinger, M. S. Suthar
This study shows SARS-CoV-2 infects human airway epithelial cultures, induces pro-inflammatory cytokines, and is inhibited by type I and III IFNs.
bioRxiv · May 19, 2020Microbiology