Microglia Morphological Response to Mesenchymal Stromal Cell Extracellular Vesicles Demonstrates EV Therapeutic Potential for Modulating Neuroinflammation
K. R. Daga, A. M. Larey, M. G. Morfin, K. Chen, S. Bitarafan, J. M. Carpenter, H. M. Hynds, K. M. Hines, L. B. Wood, R. A. Marklein
This paper demonstrates that MSC-EVs modulate microglia morphology and cytokine secretion, suggesting their therapeutic potential for neuroinflammation, and introduces a high-throughput morphological screening method for EV bioactivity.
bioRxiv · Jul 1, 2024Bioengineering