The Coxiella burnetii secreted protein kinase CstK influences vacuole development and interacts with the GTPase-activating protein TBC1D5
S. Brelle, E. Martinez, S. Huc-Brandt, J. Allombert, F. Cantet, L. Gannoun-Zaki, F. Letourneur, M. Bonazzi, V. Molle
This study identifies CstK, a Coxiella burnetii kinase, as an effector that interacts with TBC1D5 to regulate vacuole formation and intracellular replication.
bioRxiv · Apr 18, 2019Microbiology