Radiolabeled Bacterial Metallophores as Targeted PET Imaging Contrast Agents for Accurate Identification of Bacteria and Outer Membrane Vesicles in vivo
N. A. Siddiqui, H. A. Houson, S. C. Thomas, J. R. Blanco, R. E. ODonnell, D. J. Hassett, S. E. Lapi, N. Kotagiri
This paper develops radiolabeled bacterial metallophores for non-invasive PET imaging of bacteria and OMVs in vivo, achieving strain-level specificity and enabling monitoring of antibiotic treatment outcomes.
bioRxiv · Aug 6, 2020 · PreprintBioengineering