Organ-restricted vascular delivery of nanoparticles for lung cancer therapy
D. A. Bolukbas, S. Datz, C. Meyer-Schwickerath, C. Morrone, A. Doryab, D. Goessl, M. Vreka, L. Yang, C. Argyo, S. H. van Rijt, M. Lindner, O. Eickelberg, T. Stoeger, O. Schmid, S. Lindstedt, , S. Meiners
This study introduces organ-restricted vascular delivery to enhance nanoparticle targeting to lung tumors, showing improved cellular uptake compared to systemic or intratracheal administration.
bioRxiv · Mar 5, 2020Pharmacology & Toxicology