Effects of germline and somatic events in candidate BRCAness genes on breast-tumor signatures
W. R. Bodily, B. H. Shirts, T. Walsh, S. Gulsuner, M.-C. King, A. Parker, M. Roosan, S. R. Piccolo
The paper examines how germline and somatic events in BRCAness-related genes affect breast-tumor signatures, finding similarities between BRCA1/BRCA2 aberrations and other genes like ATR and BARD1.
PLOS ONE · Sep 30, 2020Peer-reviewedCancer Biology