A high-throughput 3D cantilever array to model airway smooth muscle hypercontractility in asthma
P. Beri, C. Plunkett, J. Barbara, C.-c. Shih, S. W. Barnes, O. Ross, P. Choconta, T. Trinh, B. Litvin, J. Walker, M. Qiu, S. Hammack, E. Toyama
The paper develops a 3D microtissue model of asthmatic airway smooth muscle to identify contractile modulators and validate their effects through RNAseq analysis.
bioRxiv · Oct 25, 2022Bioengineering