Simultaneous optimization of donor and acceptor substrate specificity for transketolase by a small but smart library
H. Yu, R. I. H. Lopez, D. Steadman, D. Mendez-Sanchez, S. Higson, A. Cazares-Korner, J. M. Ward, H. C. Hailes, P. A. Dalby
This paper engineers transketolase to accept novel donor and acceptor substrates, improving catalytic efficiency and stereoselectivity for industrial applications.
bioRxiv · Aug 9, 2019 · PreprintBioengineering