Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA
S. Holvec, C. Barchet, A. Lechner, L. Frechin, S. N. T. De Silva, I. Hazemann, P. Wolff, O. von Loeffelholz, B. P. Klaholz
The paper presents a 1.9 Å cryo-EM structure of the human 80S ribosome, revealing new rRNA modifications and ions, and their roles in RNA architecture and function.
bioRxiv · Nov 23, 2023 · PreprintBiochemistry